Clinical Trials

A worldwide quest is under way to find treatments to stop, slow or even prevent Alzheimer’s disease. Some of the most promising research is happening right here in San Diego. Many of the new drugs in development aim to modify the disease process by impacting the many brain changes that Alzheimer’s causes. Current trials in San Diego County range from drug research to studying the impact of sleep on cognitive decline and caregiver stress.

People with Alzheimer’s, caregivers and healthy volunteers are needed today to participate in Alzheimer’s and dementia research. When you join a clinical trial, you have an opportunity to participate in critical research that could change the course of Alzheimer’s disease and improve the lives of all those it affects. By signing up to learn more, Alzheimer’s San Diego will send you the latest information about local studies that could be a good fit for you.

We need your help. Without participation, finding a cure is virtually impossible.

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A groundbreaking local initiative that combines San Diego’s resources in order to accelerate research and drug discovery projects to find a cure.

Click to download a PDF listing or scroll down below to see a current list of trials that are actively looking for participants.

Current Research in San Diego

Thank you to our valued clinical trials partners, featured below. Their support helps keep our services free to the community.

Sharp Healthcare Clinical Research

  • AHEAD 3-45 study: The study will test the effectiveness of an experimental drug BAN2401 in people with Pre-Clinical Alzheimer’s, who are at an increased risk of developing Alzheimer’s.
  • Eli Lilly AACI: The study is investigating the safety, tolerability and efficacy of Donanemab (antibody) in patients with early symptomatic Alzheimer’s Disease to determine if removal of existing amyloid plaque can slow the progression of Alzheimer’s.
  • ATRI NIC study: The study is investigating if transdermal nicotine will produce sustained cognitive, clinical, and functional benefits for subjects with MCI.

Please note: Insurance is not required for study participation. Participants and study partners are compensated for time and travel, and transportation can be provided for each study visit. For more information call 858-836-8350 or visit www.sharp.com/clinicaltrials.

Excell Research

Excell Research is seeking volunteers with mild cognitive impairment (MCI), memory concerns and/or problems with thinking to participate in Alzheimer’s research. Free memory screenings offered at various locations.

  • AgeneBio: A double-blind, placebo-controlled study evaluating the efficacy and safety of AGB101 (low-dose levetiracetam, 220 mg, extended release tablet) on slowing progression of mild cognitive impairment due to Alzheimer’s disease.

For more information call 760-758-2222 or visit www.excellresearch.com.

Alzheimer’s Therapeutic Research Institute
(Keck School of Medicine of USC)

  • Alzheimer Prevention Trials (APT) Webstudy: An online cognitive assessment research study aimed at accelerating the enrollment time for clinical trials designed to prevent Alzheimer’s disease. The purpose of the webstudy is to develop a large online group of individuals who may be at higher risk for developing Alzheimer’s dementia, and who may be interested in participating in a prevention trial.

For more information and additional trials, call 858-964-4644 or visit www.keck.usc.edu/atri.

Additional research opportunities in San Diego County:

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